SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c9039b6d8d00466170a7ed85759bbce342f1fedc9d057c91f4008630b5cf4f2' 
  AND token = 'oJi1GPXFnh0byyk3UdPBQOaQBfbp+ZUQgTJa0qEhhZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}