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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88d25edd9cf929bfff50e816971cb8c57103cf4a9edf531d24c2837e22cd9604' 
  AND token = 'maa0TZRyXpE1TiBKOmJajliy14hC/uO0yd8L5pP+jqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}