SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6fd4da375b4cd5139c01cc96f23caeab945e2844ce4c609618a1821c5d73bd' 
  AND token = '/Ii3PwMnQARg6T2TcDLxkCLcc9SiA35L0zVTUv2Tyrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}