SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0c59dc5c4db0fabba43a3c18ca2c10929ad97b64c258356b8ce61781752288' 
  AND token = 'tPGXrwY/gSeIcIOs0P2bo7bvHyxl89peL+RZqTHfV/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}