SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84d3a6a720860b2db310a80fee7da3004f6503c8528d035e1240ab595fb7dcff' 
  AND token = 'Ai+rlTsSCuaVbIjRQ5Z26nO0QcXbtM4GzOnxeXB6JD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}