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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '837bf2ee82c107a8eb2e5f0653d5f7e176960afd0b6a63abdb0832f09bdfce5f' 
  AND token = 'l+Xkx/tLENAFfkUuGU1vcqouMd9hJDr9dowseskrW8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}