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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '279a1e899ca23f08513ce606099b9497f015cfc58e1afe234fd8997fb7f47dc8' 
  AND token = '2eDxpY1XvhpH3WKn3ppS58I5onYz/f0hm3CZsv2SeG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}