SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '244e8f5d27ba302d2a10e8235e2210a340ee1102330549548e18fcbd77802adb' 
  AND token = 'dgszvk2rO8xvc3Qp/vW5FFMbyc3c1/BEa1GVUH+lpFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}