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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6bf60f56ed581151d4a34979861bab1b5fc5b5b09f146837175e187d63ffdf' 
  AND token = '1j3LtcZhV7+sYXLLO8vUj3na8HHREMmEFoDmj/dJFpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}