SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4be58e4d59f750c324a0af7d583f1b4db8ab691e04fda379919f4e6869d7f240' 
  AND token = 'AYaHO0qHLCVDS8WwpdF4/DfgK+bTNEf+czY2sBLVuy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}