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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac5338e26228f68a3fa4ed5194c1f24c06da7d284a394478365f5b19add8ac55' 
  AND token = '2kqkLvrV8NUAQjCp8FyLlGx5T0Qt9pLW5HWjNRVZoFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}