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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '002d9ef9280244371e4f85c0406cc94f23f90a2349a32546a6a297e77b98c586' 
  AND token = '68A0WyKcMFMhhPaW2gsAQD4l8ZrcZ8lcoCNTdwC7PQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}