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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7230be7888ec1988559afc6874e3219870925bb4097889005b1fd0d010d77e8' 
  AND token = 'UQ/rFLDCSE+Ay30awpt/DWdNmKa3UjVdZgW5wfUIdP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}