SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a59f7a2ebbea2953c0973cf462f965a01a251881c09095520bb4f14034f11352' 
  AND token = 'QMYv6KWPFwIQD6DCf5cDIMc0LhZ/f5dp7DRt0dIWt2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}