SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '586c8ed44f7842b0ccd4ca3823af53a264a424ef0a29e2573fc48ded78a1f34a' 
  AND token = 'R4GtNEYydFx9zdkDSe+kxJhPLrBphxKhJ+znfZTh4Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}