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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c40e75f2f841629adbd1e4e42dee700507ced8e6f5f39cfcfde445b498d15af8' 
  AND token = '48XuTWGfxHWrKnK30jD3cn5ZM9jOIxXEee2vO9v76xA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}