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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de77e4ccb0d622d1e15285825c6c56f12f4fb2b6814a4ea9e480a91822520f60' 
  AND token = 'HHIr9xZNpqJN44buD1in7t0hDke8d0Tb3ZCgVZhpYW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}