SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '865d94b6a61a3b2e4e069d0566a60a578de1c80bb350a4bd1a68f0d9191694e6' 
  AND token = 'amSAm/KwWk9FVziKxQP0MZVQgvNll2BjYqkUY0cyrNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}