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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '423f1ef1a6ed5947da715dce3fbd23ed35a276ab2d649db79bced3cfa8d953b9' 
  AND token = 'PqNjv7+olqjylW5kOPskWwBJyK02kEms6J/407bNV0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}