SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09e193cca5b1fbd35e1aea9f6e1773203021753ba74ffb35f569d4ca63347d92' 
  AND token = 'yST9Z9gWDF9HhdemkcAHGLBgVxlaKdVT9hDC+KZ1lLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}