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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deb7d7ac11cba284f71ede421a8d824d684a8f5ad6d4ee442daa8bb61098a774' 
  AND token = 'cEsAD/NPRllh/kPR0MlEOzCNiB0sxFBdbOK53PFOkW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}