SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52312db1b96355b6829e21ff2cc8c3bb6d2a71bc057f12bb2468ec4b43e1ed52' 
  AND token = 'ER652e3AJ1f1GIdAZIOV4nLJzT5mVc79RPWWwHbq9NY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}