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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8502379a208cd3d2018d4e37f4c5196746c3bb50d68844f1a228d201d5f647eb' 
  AND token = '2grNb8Xx6M3S4+EXw7bJ7g2M1TWJTh8u5VJXNO5ne0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}