SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0188b6e92aa96640a470ba85d4bf5c1a55941b205d3f58647ccdfd8534dcdf' 
  AND token = 'U/CbFca0Lt+66osIIpitM6uJvs3kSJ6CIKw5/nZ9bYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}