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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed7edd754b1f23cd29db9aeb7b93f6a1fe671db81095df0cf322cce9389da8c' 
  AND token = 'zzaDc/hIYAQ3t4PVbLrXjoFETzq8kLroiDzGN35dSFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}