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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a29e7af0ce7725638e5e0c8add81fde1de08ef4c557be3203b3976e80844153b' 
  AND token = 'nFglhiCXJCb6y3/0dhYNjCM4NdzSCh2wzXLC2R0UCzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}