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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '071f96c33c7390cf7fde1f79bf15c301ea24ccc9a7e6d38104cc278ae3036c21' 
  AND token = 'jAm/QHImreK5yv6VqknUeZ+XsAZlGyU+nje7qAJGJqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}