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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e69726d2a4599f8e6dc2e727835337918eebe8073a3bcda7975143914523171' 
  AND token = 'DA5tmkFl+fT+o1LGr8qHbW/OzZ02YUf3D0yNokw79Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}