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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6591e4e633274f53e76a862b00b450088629564bfb0a6e3a8a4a35919aebb9c9' 
  AND token = 'hqzWs8dVgA/UICOaue0atv2uUJaNddZvcOmzVhuAVHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}