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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d13e64ffd8104e8b4b71e79fc7b73fa8222c8f81b969193faf5590e0287e5b0' 
  AND token = 'T1SaYeTwM7Crzf+AlyR9IrCeb8YlZoeQ9/BQ3YYhquM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}