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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '516ebe76595f9ae5a69c4f82b6c5dd89b978af3b1f128b12ace6a39cf95c822e' 
  AND token = 'EgKEoO7lUtz7hIR1SWfMsA+Q0gVwJj22LsgmcuVk128=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}