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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '621f142354bba2d37ac42c48b370f0e09255615899b9f0c085369ca4fededfb7' 
  AND token = '46AgqTu7nv+vpp3s5huDka9EkCSDOa6LCN0Ea7L0ZtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}