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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1052c7612d7ff838c975dba6b36231a9a5862793ecc109a04be4be5d720ebabd' 
  AND token = 'FjUQLWvqj/EbqDsQzpo161HMnOLPMrOmUYXlL72DhQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}