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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f17085ffe5ff1a79058537ec637abf59cda6280b644cb39f9dd0066a6455e1f2' 
  AND token = 'wp4hhs3MCBMdbPJbr9CX3DJtD3evIC/FcZLWZfGtkEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}