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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25cf5913423386d8bfeaeadfd3043cd5acde3634c26c19a6fdb22ca2eb7db91c' 
  AND token = 'y/UBtRL+9FLNiSSEwg60rHXYrCe78EfNTeqX8oC0pLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}