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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100952b85cbc6c0ab37e7832a23ca8ad45e3200d4d24626d52c453c7513486b2' 
  AND token = 'dppJodtKyAR18/cZ+oZT7sCxtzpyMy1LKn8rHzlnQ9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}