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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f63b7eb9264e07234edfb7ef3e4e8dfe30ea3d6d249fcda1ff4f115835d95d2' 
  AND token = '+JEu36WaZbUEe07XyQcwJdGFkdp4zhr8l5yan2W/d0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}