SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64cbfdbd7f975df44910c5d944b43ec60053ac834f51aa5131a66ae596160003' 
  AND token = 'SmIYqo/5lP85mp0xP6Ahg+ftCYbdr6o6QczzK281fOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}