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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e78aa6beaec44734ed3f20e7a70840b69b952e9e4852ff422f3e1053552b6b4' 
  AND token = '53R4fUE/kyxTZDx0ZxMozzF5OAp51TY+cUrf10si9Og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}