SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b054241e173cb8e218a705e3907f2db60fd88424a1ce357ae42dc4a8626b4c29' 
  AND token = 'QM6Lhb2hLoLHxoSgg5y///cGRM+3rMvVncTX9oNi6PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}