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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7752a81be4c9486f59828da9c50d4ecb0dd63d50b4baca4385835377a5fb33d2' 
  AND token = 'ep8Nu20PAmATuEHLgIiL/iKmxBOnc9OKOTpdJIqDErM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}