SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13d296e78784fb6f6f6a7bc92e90e895deb41e9229fe6e5571330cfa8b82c6ed' 
  AND token = 'E+M8SsQu2Q4aJOUEL8BuITKFJW84bpiweWVmuuQS+5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}