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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '316d236064c64861cf6f07e7c8de42253d14061f6865b993598a71bfffb90f0e' 
  AND token = '975+4P0lYe+uS2MsxFIdzImnfhc/lihpAsjPC5m/LtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}