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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0e930b88c24f7bf2a00af3db2de40345227df9a83193c1aa80b5ddc8c9f304' 
  AND token = 'dIW0z4sJtyRiEi+BD1zGYbG8I6ymHS6H9D2VFcRrZJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}