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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85245d6f50304ec21a4984b9fcddbb27a1d0128576618766f64c168a5798ded1' 
  AND token = 'gdFJ7edkITM1p+VtguCE0ZC31+DN9uxyX7U33bGBbZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}