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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f7681b1b2eea30c037a64de8ea4bcd78dfd79f02b4c51aaa946f534075fdabc' 
  AND token = 'XN2ix1cM6a6jmPoO3NVD+n6F8QkvziTm+oYi3ByYlts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}