SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cbbe5007e48aae7d007a3ae6fc72cb7df4a85f6a29188af3e353cf91eb0b5cd' 
  AND token = 'JBVBoy3k7JjqknTGz3OZUvWicIvMbbcdZpeP0a7TQAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}