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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff5e89a5dd1fb7027dca04bbd32c61ad8e568ee77c1e8b0dce23780567edd37' 
  AND token = 'UpQAJ+xZwc4dBbxT03TuUX0/0o02zHYudHU3CjV5Dus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}