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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3c927899dac2aabc2cc28b432aa6f69e0a8ff41d3631cf534e760114f6ae1d2' 
  AND token = 'LeAR2BipucTsiC9b9GlC5qD3EFfJ53C3UiHJ2zWIVd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}