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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '189ef336c4c70d5a48e971186b5935d1946a94a4c11574bb00131806cf95abed' 
  AND token = '4ggk65taCpA5k973IT+mn82xUx1BwbzNU1ryQuizT1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}